Pathology Handbook

PLEASE NOTE: Recent changes have been made to this Test

Recent changes for Voltage gated K+ Channel Antibody

Recent changes for Voltage gated K+ Channel Antibody
Date	Field	Changed From	Changed To
2nd September 2026	Alternative names	Anti-VGKC	Anti-VGKC, Encephalitis Ab

Voltage gated K+ Channel Antibody

Alternative Names:

Anti-VGKC
Encephalitis Ab

Laboratory:

Haematology

Test Code:

VGKC

Specimen Types:

Serum

Container Types:

SST

Adults Volume or Mass:

10 mL

Minimum/Paediatric Volume or Mass:

1 mL

Collection & Request Instructions:

Associated with Acquired neuromyotonia and Limbic encephalitis-like syndromes.

Please include all the provisional, diagnosis or clinical signs.

Transport Instructions between Sites and/or Laboratories:

Room Temperature

External Laboratory:

Pathology Queensland- RBWH Campus

Additional Notes:

VGKC can be tested on serum samples. VGKC test request will additionally have LG1 and CASPR2 indirect immunolfluorescence testing performed if VGKC is positive.

VGKC cannot be evaluated on CSF with the current assay method, VGKC RIA. However, LG1CSF and CASPR2CSF results will be reported for CSF samples sent for VGKC testing.

Please refer to Alfred Immunology scientists for clarification.

Pathology Handbook

PLEASE NOTE: Recent changes have been made to this Test

Alternative names

Voltage gated K+ Channel Antibody