Pathology Handbook

PLEASE NOTE: Recent changes have been made to this Test

Recent changes for Prothrombin G20210A Mutation

Recent changes for Prothrombin G20210A Mutation
Date	Field	Changed From	Changed To
6th May 2026	Optional Container Type		EDTA 3 mL
5th May 2026	Volume (Adults)	3 mL	2.7 mL
	Minimum/Paediatric Volume		1.0 mL
	Preferred Container Type	EDTA 3 mL	Sodium Citrate
	Frequency	Fortnightly	Weekly

Prothrombin G20210A Mutation

Alternative Names:

Prothrombin Gene
PT Gene
G20210A
PTGM

Laboratory:

Human Molecular

Test Code:

PT GENE

Specimen Types:

Blood

Container Types:

Sodium Citrate
EDTA 3 mL

Adults Volume or Mass:

2.7 mL

Minimum/Paediatric Volume or Mass:

1 mL

Collection & Request Instructions:

For identification of carriers of inherited venous thrombophilia. General population screening and routine screening before prescribing oral contraceptives or hormone replacement therapy are not recommended. Test should only be requested by a practioner skilled in genetic counselling of thrombophilia. The significance of a polymorphism in an unaffected individual is uncertain.

Transport Instructions between Sites and/or Laboratories:

Room Temperature

Assay Frequency:

Weekly

External Laboratory:

Melbourne Health Shared Pathology Service

Additional Notes:

EDTA or Citrate to Royal Melbourne Hospital for AH and WH patients

Citrate only to Monash health for MH patients

Pathology Handbook

PLEASE NOTE: Recent changes have been made to this Test

Optional Container Type

Volume (Adults)

Minimum/Paediatric Volume

Preferred Container Type

Frequency

Prothrombin G20210A Mutation