Pathology Handbook

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Sirolimus

Laboratory:Clinical Biochemistry
Test Code:SIRO
Specimen Types:Blood
Container Types:
EDTA 3 mL
Collection & Request Instructions:Collect pre-dose
Retrospective testing within 7 days
Transport Instructions between Sites and/or Laboratories:Room Temperature
Assay Frequency:Daily
Additional Notes:

Therapeutic Ranges (Pre Dose):

  Heart Transplantation
    < 12 mth     10—15 ug/L
    >12 mth        5—10 ug/L

  Lung Transplantation
                        6—13 ug/L

  (Lower levels for Heart & Lung when used with Calcineurin Inhibitors.)

  Kidney Transplantation
                        6—11 ug/L

  Bone Marrow Transplantation
                        5—10 ug/L

 

LCMSMS Methodology from 12 December 2009.