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Pro-Brain Natriuretic Peptide

Alternative Names:NTBNP
Pro-BNP
Laboratory:Clinical Biochemistry
Test Code:NTBNP
Specimen Types:Blood
Container Types:
Lithium Heparin (with Gel)
SST
Adults Volume or Mass:4 mL
Minimum/Paediatric Volume or Mass:1 mL
Transport Instructions between Sites and/or Laboratories:Room Temperature
Assay Frequency:24/7
MBS Rebatable:Yes
MBS Item No.:66829
Billing Information:

Also MBS Item Nos 66830, 66585, and 66586

Additional Notes:

Test is performed on Abbott Alinity

Reference Intervals:

The recommended NT-ProBNP cut-off value to rule-out heart failure is < 300 ng/L

The age-related cut-off values for NT-ProBNP to rule-in heart failure are:

Age <50 years:     >450 ng/L

Age 50-70 years: >900 ng/L

Age >=75y years: >1800 ng/L

 

Reference: Adapted from the 2018 National Heart Foundation of Australia and Cardiac Society of Australia and New Zealand guidelines (Atherton et al.  Heart, Lung and Circulation 2018;27:1123).

 

MBS Indications:

NT-ProBNP is MBS-rebatable for the following indications:

1.For the diagnosis of heart failure in patients presenting with dyspnoea to a hospital Emergency Department

2. Testing in a patient with systemic sclerosis (scleroderma) to assess risk of pulmonary arterial hypertension (Maximum of 2 tests in a 12 month period)

3. Testing in a patient with diagnosed pulmonary arterial hypertension to monitor for disease progression (Applicable 4 times in any 12-month period)