Must be approved by Chemical Pathologist
This is a non-MBS test. Cost is $50
Results interpretation
A random copeptin of >/= 21.4 pmol/L is consistent with nephrogenic diabetes insipidus.
In the setting of hypernatremia, a copeptin <4.4 pmol/L is consistent with central diabetes insipidus.
In a hypertonic saline infusion test, once plasma sodium is >/= 147 mmol/L, a copeptin of >4.9 pmol/L suggests primary polydipsia and a copeptin of < and = 4.9 pmol/L is consistent with central diabetes insipidus.
Reference:
Christ-Crain et al, J Clin Endocrinol Metab 2022; 107: 1727-38.
Test performed on a BRAHMS Kryptor Compact PLUS at Northern Pathology Victoria from 15/12/2022. |