Ref. Range: 14 -20 mg/L
Serum Mitotane levels above 14 mg/L are associated with optimal therapeutic effect (Haak HR, et al. Br J Cancer 1994.69:947-951). Levels above 20 mg/L are associated with toxicity, mainly gastrointestinal and CNS adverse effects (Van Slooten H et al. Eur J Clin Oncol 1984. 20: 47 - 53, Baudin E et al. Cancer 2001. 92:1385-92).
Note: This test is not Medicare funded. Assay performed by a non NATA accredited research lab- Medical Oncology laboratory at Calvary Mater Newcastle Hospital.