Pathology Handbook

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Troponin I

Alternative Names:

TnI

Laboratory:

Clinical Biochemistry

Test Code:

TROPONIN

Specimen Types:

Serum
Plasma

Container Types:

SST
Lithium Heparin (with Gel)

Collection & Request Instructions:

Retrospective testing within 7 days

From 2/7/2013 Cardiac Troponin I is measured with the Abbott Architect high sensitvity assay with improved low end precision. The units have changed from ug/L to ng/L, giving troponin I values 1000-fold higher than previously. Gender specific 99th percentiles are <27ng/L for men and <17 ng/L for women. Elevated troponin I is indicative of myocardial injury but does not identify the aetiology. Higher troponin I values even below the 99th percentile are associated with worse long term (years) outcome.

Transport Instructions between Sites and/or Laboratories:

Room Temperature

Additional Notes:

Reference Range: Males < 27 ng/L
Females < 17 ng/L

Elevated levels associated with cardiac disease are an independent predictor of mortality.

A persistent elevation of Troponin I which is not consistent with the clinical picture can be due to heterophile antibodies interference. Please contact the laboratory for further tests to exclude this interference.