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PLEASE NOTE: Recent changes have been made to this Test


 Recent changes for Voriconazole

Recent changes for Voriconazole
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Voriconazole

Laboratory:Clinical Biochemistry
Test Code:VORI
Specimen Types:Plasma
Container Types:
EDTA 10 mL
Adults Volume or Mass:5 mL
Collection & Request Instructions:Collect pre-dose

Assay run 3 x weekly  (Monday, Tuesday & Thursday) - samples must be in lab by 11AM on each day.                               Results available at the end of the day.

Transport Instructions between Sites and/or Laboratories:Room Temperature
Assay Frequency:3 x weekly (thrice)
Additional Notes:

Therapeutic Range for Voriconazole

Monitoring Voriconazole trough concentration at steady state (after one week of initiation or change of therapy) can be clinically helpful. 

Suggested therapeutic range is: 1 - 5.5 mg/L.  Trough concentrations < 1 mg/L suggest inappropriate absorption and concentrations > 5.5 mg/L have been associated with toxicity.

(Dodds Ashley E and Perfect JR. Pharmacology of Azoles. UpToDate (accessed online 12/7/10)

Refer to Alfred PROMPT Voriconazole guideline for further details