Pathology Handbook

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Cholinesterase

Alternative Names:

Pseudocholinesterase
Dibucaine Number
Fluoride Number

Laboratory:

Clinical Biochemistry

Test Code:

CHESTERASE

Specimen Types:

Blood

Container Types:

EDTA 4 mL
and
Lithium Heparin (without Gel)

Adults Volume or Mass:

5 mL

Collection & Request Instructions:

In cases where prolonged apnoea follows suxamethonium administration an assessment of atypical cholinesterase can be made using the Dibucaine and Fluoride Numbers. Such assessment should not be made until 24 hours after suxamethonium administration.

Avoid haemolysis.

Note Additional Collection Instructions:

Pathology Queensland prefer to receive BOTH a Lithium Heparin Plasma (no gel or gel) specimen PLUS a 4 mL EDTA whole blood sample. (EDTA specimen must be sent unspun).

Transport Instructions between Sites and/or Laboratories:

On Ice

Assay Frequency:

Weekly

External Laboratory:

Pathology Queensland- RBWH Campus